WRONG WRONG WRONG.
Northern exposure and twin peaks lost their way (and you're speaking to someone who's drunk a beer in the brick and coffee in the Double R.) Six feet under lost it's way so badly for so long (although the David carjack episode is outstanding)
Deadwood is excellent. As is the sopranos. But neither stands shoulder to shoulder to the wire. The wire doesn't do stand alone. It doesn't do dream sequences, it avoids stand alone episodes. Flash backs, any kind of narrative trick to keep it "interesting" fuck it. Five years and five montages ever other piece of music is incidental.
The wire does five years of straight up narrative, no clever tricks, no short cuts, no ease tv cliches. If you honestly want to compare the wire to sopranos check out the episode the FBI try to plant a bug in Tony's basement v the series long struggle the crew in the wire have over bugging cell phones and pay phones, and how amazingly satisfying these arguments and debates are.
For ever juror with delusions of forensic ability after getting a CSI boxed set. After watching the wire, well, just give it up.